Luciano Canfora, "Gli antichi ci riguardano"
نویسندگان
چکیده
منابع مشابه
Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling.
Hedgehog (Hh) signaling plays essential roles in animal development and tissue homeostasis, and its misregulation causes congenital diseases and cancers. Regulation of the ubiquitin/proteasome-mediated proteolysis of Ci/Gli transcription factors is central to Hh signaling, but whether deubiquitinase is involved in this process remains unknown. Here, we show that Hh stimulates the binding of a u...
متن کاملLuciano Floridi
This paper may be read as a sequel of a 1995 paper, published in this journal, in which I predicted what sort of transformations and problems were likely to affect the development of the Internet and our system of organised knowledge in the medium term. In this second attempt, I look at the future developments of Information and Communication Technologies and try to guess what their impact on o...
متن کاملLuciano Antonio
Construindo o " pacto de gestão " no SUS: da descentralização tutelada à gestão em rede Abstract Over time, the implementation of Bra-zil's National Health System (SUS) has encountered management problems. Initially, steadily rising pressures calling for State reform and trim-mer costs affect the universal healthcare that is the purpose of this system. Conflicts then flare up between the decent...
متن کامل- Luciano Barbosa
For the past ten years, I have worked on several problems related to finding and organizing Web data. From 1999 to 2002, I was a lead developer for Radix, one of the first Brazilian search engines. During my Masters, I designed and implemented a Web crawling policy that uses classification techniques to efficiently update a search engine index while maximizing its freshness [11]. After finishin...
متن کاملSuppressor of fused impedes Ci/Gli nuclear import by opposing Trn/Kapβ2 in Hedgehog signaling.
The Hedgehog (Hh) family of secreted proteins governs many key developmental processes by regulating Ci/Gli transcription factors at multiple levels including nuclear-cytoplasmic shuttling. Here, we investigate the mechanism underlying the regulation of Ci/Gli subcellular localization by identifying and characterizing a novel nuclear localization sequence (NLS) in the N-terminal conserved domai...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Storicamente
سال: 2016
ISSN: 1825-411X
DOI: 10.12977/stor628